The name for the village comes from the Latin word "Limen", which means border. Surrounded by mountains and water the economy was traditionally based on fishing, olives and lemons. Then in 1932 the Gardesana Occidentale was completed and at last isolation came to the end.
After the world wars tourism started. The inhabitants started to transform the little fishing village into a tourist resort, which is now one of the most important ones at Lake Garda.
Limone became famous in 1979 when the APOLIPOPROTEIN A-1 MILANO was discovered. This protein, which is in the blood of the people born in Limone, quickly removes the fat from the arteries. This protein is efficacious against arteriosclerosis and infarct.
Limone is the Italian word for 'lemon' and this shore of Lake Garda was once renowned for growing lemons and other citrus fruits. Limone's name, however, is no more than a happy chance, since it is said to be much older than the lemon groves, and to derive from a Latin word meaning 'boundary'. The town is still close to a boundary: between Italian regions. Lake Garda is shared by three Italian regions; Limone is part of the province of Brescia, in the Lombardy region. It is known as Limone sul Garda, to distinguish it from another Limone (in Piemonte).
Parts of the 2008 James Bond movie Quantum of Solace were filmed around Limone, although the shoot was dogged by bad luck and talk of a 'curse'. Scenes include a car chase along the lakeside road, the Via Gardesana